Prospective Multicenter Study Assignment Sample

Critical Appraisal

Critical Appraisal of - Head-to-head comparison of the diagnostic performance of coronary computed tomography angiography and dobutamine-stress echocardiography in the evaluation of acute chest pain with normal ECG findings and negative troponin tests: A prospective multicenter study

The research objective is to perform a comparison in two types of patients presenting chest pain in recent times considering their ECG and troponin are negative. The article was recently published in 2017. The article states a strong influence on methods, results, and discussion. The article has been peer-reviewed by other authors as well. There have been five detected peer reviews in the article. In the research paper, no hypothesis has been reflected. No such argument has been generated. However, the method has been given along with the resulting providing the conclusion on the evaluation between two categories and which one has a higher diagnostic performance.

The multicenter study approach has been used in the study. The patient selection process has been conducted very specifically by reflecting on democracy and the chest pain health issue among the patients. Index texts have been organized with two categories that have to be compared. Then, the reference test and patient follow-up were performed and statistical analysis has been carried out by the standard deviation method. Accordingly, and critically reviewing the same; it can be said that the method and the design of the multicenter approach used in the research study have been following principals set out in the Declaration of Helsinki (Durand et al, 2017). Also, it supports the research in a conclusive format. The kind of research has a limited scope of possible biases as the demography of the study has been very selective and the criteria have been closed-ended while deciding on the patient-facing the chest pain issue. The research method has been confoundingly and variably influencing according to the research objective. Standard deviation measures will be appropriate to calculate the health conditioning as per the research.

The research has been carried out and been written in a very specific manner. It even consists of a table for the demographics for the groups similar. The authors did not generalize on their patients. Every aspect has been covered also the statistical test of standard deviation which comes out to be appropriate stating the kind of research design and clinical question.

The part of stating on findings and the results are a bit missing and could have been significantly showcased in the research paper.

The research paper has significantly provided a conclusion that is clear enough to understand. Limitations and assumptions used in the research should have been highlighted with a greater impact to make the research more relevant. 

References for Prospective Multicenter Study

Durand, E., Bauer, F., Mansencal, N., Azarine, A., Diebold, B., Hagege, A., ... & Bensalah, M. (2017). Head-to-head comparison of the diagnostic performance of coronary computed tomography angiography and dobutamine-stress echocardiography in the evaluation of acute chest pain with normal ECG findings and negative troponin tests: A prospective multicenter study. International Journal of Cardiology, 241, 463-469.

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